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Names |
History |
Constituents |
Uses |
---|---|---|---|
Onagraceae Family,
|
Used traditionally as a food by North American tribes,
the root was boiled and the flowers used as a sweet in salads.
|
Gamma-Linolenic Acid (GLA) -9.7%,
|
PMS |
Possible Interactions
Veratrum alkaloids may potentiate the activity
of evening primrose by up to 50%.
The hypotensive effect of this
herb may also be potentiated by anorectic drugs such as fenfluramine,
whose effects are mediated by brainstem 5HT.
Evening Primrose should
not be used with methotrimeprazine, a potent CNS-depressant analgesic.
Furthermore, colchicine may increase sensitivity or enhance the response
to evening primrose.
The topical application of this astringent herb,
in conjunction with the acne product tretinoin (retinoic acid, vitamin A
acid), may adversely affect the skin.
Additive effects may
occur between the hypotensive property of evening primrose and that
of dopamine receptor agonists, such as bromocriptine mesylate.
It is active against Staphylococcus citrius, S. roseus, Pseudomonas pyocyanea, Streptococcus pyogenes, E. coli, Bacillus subtilis, Klebsiella aerogenes*, Diplococcus pneumoniae and Salmonella typhi. For each of these organisms, the oil compared favourably with penicillin.
Due to the presence of blood serum platelet aggregation
inhibitors, such as linolenic acid, evening primrose may potentiate
the effects of anticoagulant drugs such as heparin.
In order to minimize
central nervous system depression and possible synergism, Evening
Primrose should not be taken by persons on procarbazine antineoplastic
drugs.
Patients with a history of epilepsy should avoid evening primrose
oil as it may lower their threshold for seizures.
Also, those taking
phenothiazines for schizophrenia should use evening primrose oil with
caution as it may precipitate epilepsy.
The most common side-effects
reported in trials are headache and mild nausea.
* Klebsiella aerogenes is linked to the medical dictionary definition
Aerogenes are gas -producing micro-organisms, or baccili
Evening Primrose - Safety Factors &Toxicity
The toxicity of Evening Primrose appears to be very low.